5 Amino 1MQ (10mg)

Nomenclature & Synonyms The compound known as 5-Amino-1MQ is chemically referred to as 5-Amino-1-methylquinolinium . There are no widely reported specific research or development codes associated with this compound in public literature. It is structurally derived from quinolinium compounds. Structural Characteristics 5-Amino-1MQ is not a peptide and does not have an amino acid sequence. Its structure includes a quinolinium core with a methyl group at the first position and an amino group at the fifth position, which is crucial for its activity. It does not possess peptide bond modifications, such as N-terminal acetylation or C-terminal amidation, but the presence of the amino group is central to its functional properties. Molecular Pharmacology 5-Amino-1MQ targets the enzyme nicotinamide N-methyltransferase (NNMT) , and it acts as an inhibitor. Its inhibition mechanism has been primarily associated with downregulating the methylation pathway, affecting NAD+ and energy metabolism. Currently, detailed EC50/IC50 values are not broadly documented in literature. The compound has been shown to alter metabolic pathways related to nicotinamide-adenine-dinucleotide (NAD+) levels and sirtuin signaling. Research Applications First synthesized and described in the early 2000s, 5-Amino-1MQ has primarily been investigated in cellular models related to metabolic studies. Studies have demonstrated its impact on modulating metabolic rate and energy expenditure in vitro. Investigations focus on its role within systems where nicotinamide metabolism is critical. Technical Properties 5-Amino-1MQ is soluble in dimethyl sulfoxide (DMSO) and can be solubilized at concentrations up to 10 mg/mL for experimental applications. For stability, the compound should be stored in a dry, light-protected environment and reconstituted solutions should be used promptly to ensure efficacy. Lyophilized powder remains stable under recommended storage conditions. Compliance For laboratory research use only. Not for human or veterinary use. Not intended for diagnostic, therapeutic, or preventive applications.

5 Amino 1MQ (50mg-60)

Nomenclature & Synonyms The chemical name for 5 Amino 1MQ is 4-Amino-2-(2,6-dimethylphenyl)-1H-quinazolin-6-one. It is referenced in research contexts without specific codes identified in the literature. The compound is derived from the core structure of quinazolinone, commonly studied for their various biological activities. Structural Characteristics 5 Amino 1MQ is not a peptide and thus does not have an amino acid sequence; it is instead a small molecule chemical compound. The structure is a quinazolinone derivative with a specific amine modification at the 5 position of the quinazolinone ring. Molecular Pharmacology Research into 5 Amino 1MQ focuses on its potential to influence nicotinamide N-methyltransferase (NNMT) activity. This enzyme is involved in various cellular metabolic pathways, and its modulation can impact cellular processes such as energy metabolism. Specific receptor targets are not identified, but its inhibitory effect on NNMT has been a point of study. Research Applications 5 Amino 1MQ has been investigated for its role in modulating cellular energy metabolism via NNMT inhibition. Studies have demonstrated its potential effects on adipocyte biology and related metabolic pathways. Technical Properties 5 Amino 1MQ is soluble in organic solvents such as DMSO. It has been reconstituted at concentrations suitable for in vitro assays. Stability data indicates that the compound retains activity in its lyophilized form when stored appropriately, with recommendations for light protection. Compliance For laboratory research use only. Not for human or veterinary use. Not intended for diagnostic, therapeutic, or preventive applications.